Chantelle A. Robitaille1, Akemi G. King1, Christina A. Buchanan1, Lance C. Dalleck1. The Effects of Delayed Ischemic Preconditioning on Performance and Recovery in Repeated Cycling Bouts1High Altitude Exercise Physiology Program, Western Colorado University, Gunnison, CO, USA.


Introduction: Ischemic preconditioning (IPC) is a technique of systematically occluding and reperfusingblood vessels that has shown to induce a biochemical cascade that increases the availability of nitric oxide (NO) and adenosine and enhances blood flow, endothelial function, and ATP regeneration. IPC has two physiological windows of protection; the first(immediate) window take place within the first 12 hours of treatment, while the second (delayed) takes place 24-72 hours post-treatment. The aim of this study was to evaluate its effects cyclists performing repeated incremental cycling bouts. Methods: In a randomized, crossover study, subjects received a 4 x 5min bilateral IPC treatment to the thigh. 24 and 48 hours after treatment, they performed an incremental cycling trial, followed by a 15-min recovery period, and then repeated the same cycling trial and recovery period. Time to fatigue (TTF) was recorded for each trial and heart rate (HR), blood lactate (La-), and blood Results: pressure (BP) were recorded throughout the recovery period. Despite individual variability, delayed IPC improved TTF (p<0.05), decreased performance decrement between trials, lowered HR and BP (p<0.05), which allowed cyclists to work at higher lactate levels (p<0.05). Conclusions: These results suggest that delayed IPC may be an effective performance and recovery strategy for endurance athletes.